*POSTDOCTORAL POSITIONS*
i) Systems Biology/Circadian Rhythms
ii) Biomedical Engineering/Diabetes
/Departments of Chemical Engineering and Biomolecular Science &
Engineering
University of California, Santa Barbara/
There are two project openings, to be filled immediately, in the
following areas:
*i) Systems Biology of Coupled Oscillations in Circadian Rhythm
Generation (NIH funded)*
The proposed research will yield an improved understanding of the
organizational principles of coupled biological oscillators and provide
insights into circadian disorders that adversely affect human sleep,
physiology and cognitive functioning. The assembled research team is
comprised of an experimental biologist with expertise in the
intracellular and intercellular processes responsible for mammalian
circadian rhythm generation and synchronization, chemical engineers with
expertise in developing and analyzing mathematical models of gene
regulatory and signal transduction networks and of large systems of
coupled biological oscillators, a numerical analyst with expertise in
deterministic and stochastic simulation and the development of
professional grade simulation codes, and an applied mathematician with
expertise in large interacting systems and nonlinear stochastic partial
differential equations.
*ii) Control Algorithm Design for an Artificial Pancreas (NIH and JDRF
funded)*
This project seeks to combine continuous glucose sensing with automated
insulin delivery in a closed-loop system in order to achieve glucose
normalization in subjects with type 1 diabetes. The end result of this
line of research will be an artificial pancreas that will provide
around-the-clock glucose regulation through electronically-controlled
short- and long-term insulin delivery in response to detected patterns
of change in glucose levels. Algorithm design and mathematical modeling
are aims for the engineering component of the project. The project
involves collaborations with medical doctors who will conduct the
clinical trials.
Candidates for either position should have a Ph.D. Degree in Chemical
Engineering, Bioengineering, or related disciplines with experience or
extensive exposure to mathematical modeling, systems biology, control
and dynamics. Strong oral and written communication skills are a requisite.
UCSB offers competitive salary and benefits. Applicants should send a
CV, a statement of their professional interests (not longer than 1 page)
and the names, e-mail addresses of at least three technical references to:
Professor Francis J. Doyle III
Department of Chemical Engineering
University of California, Santa Barbara
Santa Barbara, CA 93106-5080
Submission of application material by e-mail is strongly encouraged.
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